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RELATIONSHIP BETWEEN STRUCTURE AND ANTI-COAGULANT ACTIVITY OF COUMARIN DERIVATIVES

✍ Scribed by ARORA, R. B. ;MATHUR, C. N.

Book ID
117955488
Publisher
Wiley (Blackwell Publishing)
Year
1963
Weight
647 KB
Volume
20
Category
Article
ISSN
0366-0826

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Quantitative structure-activity relation
Quantitative structure-activity relationship of coumarin derivatives : Involvement of partition between aqueous and membrane phase
✍ Reiner Düren; Horst A. Diehl 📂 Article 📅 1988 🏛 Elsevier Science 🌐 English ⚖ 567 KB

In order to understand the substrate behaviour of several 7-alkoxycoumarins and 7-alkoxy-4-alkylcoumarins towards the liver microsomal monooxygenase system, their lipophilic properties have been examined. As a model for the lipophilicity the reversed-phase liquid chromatographic retention parameter