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Relationship between steroid hormone contraceptives and HPV, cervical intraepithelial neoplasia and cervical carcinoma

✍ Scribed by Ethel-Michele de Villiers

Publisher
John Wiley and Sons
Year
2003
Tongue
French
Weight
69 KB
Volume
103
Category
Article
ISSN
0020-7136

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✦ Synopsis

Abstract

Available data demonstrate an increase in the transcription of high‐risk papillomaviruses by the 16α‐hydroxylation of estrogens, which is in line with the epidemiologic data showing an increased cervical carcinogenesis risk for long‐term contraceptive‐using, HPV‐infected women. No evidence exists for an increase in HPV‐negative contraceptive users. © 2002 Wiley‐Liss, Inc.

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