✦ LIBER ✦

Relationship between previous reproductive history and chemically induced mammary cancer in rats

✍ Scribed by Richard C. Moon

Book ID: 102274489
Publisher: John Wiley and Sons
Year: 1969
Tongue: French
Weight: 423 KB
Volume: 4
Category: Article
ISSN: 0020-7136
DOI: 10.1002/ijc.2910040308

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✦ Synopsis

The relationship between a previous history of n?irltiple pregnancies and/or lactations and 7,12-diniethylbenz(a)anthracene-induced nianimary carcinogenesis was studied in groups of Sprague-Dawley rats. All rats received the carcinogen at approximately 6% months of age. Virgin control rats which did not receive the carcinogen did not develop maniwiary cancer within 13 months although carcinogcw-fed virgin rats exhibited a mammary cancer incidence of 38.5 x,. A single pregnancy prior to feeding the carcinogen r e d t e d in a decrease in the incidence and an increase in the mean time of

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