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Relationship between metabolism and cytotoxicity of ortho-phenylphenol in isolated rat hepatocytes

✍ Scribed by Yoshio Nakagawa; Sumiko Tayama; Gregory A. Moore; Peter Moldéus

Book ID
115782699
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
724 KB
Volume
43
Category
Article
ISSN
0006-2952

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Cytotoxicity of chloroquine in isolated
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✍ Akram Jamshidzadeh; Hossein Niknahad; Hamed Kashafi 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 107 KB

## Abstract Chloroquine is a synthetic quinoline being used as an antimalaria and antirheumatoid agent. Several cases of hepatotoxicity have been reported with the use of chloroquine. However, the mechanism(s) of its hepatotoxic effect is unknown. The purpose of this study was to investigate the cy