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Relationship between in vivo mitomycin c exposure, sister chromatid exchange induction and in vitro mitogenic proliferation. II. Effect of aging on spleen cell mitogenesis and sister chromatid exchange induction

✍ Scribed by Paul L. Mann; Donald E. Kern; David Kram; Edward L. Schneider

Book ID
119025237
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
365 KB
Volume
17
Category
Article
ISSN
0047-6374

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## Abstract Frequencies of sister chromatid exchanges (SCE) were analyzed in bone marrow cells of mice injected with mitomycin C (MMC) both before and during infusion with bromodeoxyuridine (BrdU). Administration of MMC at 1, 6.5, and 13 hours after the onset of BrdU infusion resulted in the induct