Relationship between GSTM1 and GSTT1 polymorphisms and schizophrenia: A case–control study in a Tunisian population
✍ Scribed by Monia Raffa; Ramzi Lakhdar; Meriem Ghachem; Sana Barhoumi; Mohamed Taher Safar; Besma Bel Hadj Jrad; Amel Haj Khelil; Abdelhamid Kerkeni; Anwar Mechri
- Book ID
- 119241487
- Publisher
- Elsevier Science
- Year
- 2013
- Tongue
- English
- Weight
- 255 KB
- Volume
- 512
- Category
- Article
- ISSN
- 0378-1119
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## Abstract Glutathione S‐Transferases (GSTs) are a family of phase II enzymes involved in the detoxification of potential carcinogens and provided of a strong antioxidant function by neutralizing electrophiles and free radicals. The __GSTM1__ and __GSTT1__ isoenzymes exhibit deletion polymorphisms
## Abstract Cytochrome P‐450 CYP1A1 is involved in the metabolism of polycyclic aromatic hydrocarbons (PAHs) that are derived from meat intake and tobacco smoking. Expression of the __CYP1A1__ gene is induced by compounds present in cruciferous vegetables. The glutathione __S__‐transferases play a