It is often believed that the frequency of clinical chorioamnionitis in preterm premature rupture of membranes (PROM) increases with the duration of the interval between membrane rupture and delivery. We tested the hypothesis that the prevalence of histologic evidence of intrauterine infection incre
Relationship between endomyometritis and the duration of premature membrane rupture
✍ Scribed by Cazip Üstün; Arif Kökçü; Erdal Çil; Bedri Kandemir
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 323 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1057-0802
No coin nor oath required. For personal study only.
✦ Synopsis
In this study, correlation between duration of premature rupture of the membranes (PROM) and the degree of membrane, decidua, and myometrium infections were histologically investigated. The study was carried on 61 women with term pregnancy (30 with PROM, 31 control group). During cesarean section, a full-thickness biopsy specimen of the uterine wall from serosa to decidua was obtained with scissors. Chorioamnionitis was histopathologically identified by neutrophilic leukocyte (NL) infiltration of the membranes. Endometritis or myometritis were diagnosed when the acute inflammatory process extended to the decidua or the myometrium successively. It was found that the presence and depth of NL infiltration significantly correlates with the interval between rupture of membranes and termination of pregnancy.
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