✦ LIBER ✦

Relationship between DNA synthesis and cell density in normal and virus-transformed cells

✍ Scribed by A. Macieira-Coelho

Publisher: John Wiley and Sons
Year: 1967
Tongue: French
Weight: 385 KB
Volume: 2
Category: Article
ISSN: 0020-7136
DOI: 10.1002/ijc.2910020404

No coin nor oath required. For personal study only.

✦ Synopsis

Three normal human and two normal bovine fibroblastic lines were compared with one of the human lines transformed with Rous sarcoma virus ( R S V ) , one human line transformed by Simian virus (SV 40) and the two bovine lines transformed with RS V, with respect to DNA synthesis between subcultivation and cell crowding. It was found that the rate of D N A synthesis during a 24-hour period was higher in the transformed cells at the terminal cell density of the respective normal lines. The results gave further support to the previous suggestion that '' unrestrained growth transformation " can be expressed by comparing DNA synthesis with cell density. In one of the transformed cultures DNA synthesis stopped at a cell density twice that of the controfs.

📜 SIMILAR VOLUMES

A comparison of DNA binding proteins fro

A comparison of DNA binding proteins from normal and virus-transformed mouse cells

✍ Victor Rubio; Wen-Po Tsai; Kenneth Rand; Cedric Long 📂 Article 📅 1973 🏛 John Wiley and Sons 🌐 French ⚖ 399 KB

## Abstract Proteins from normal and virally transformed mouse cells, capable of binding to calf thymus DNA, were isolated and compared by DNA cellulose chromatography and sodium dodecyl sulfate polyacrylamide gel electrophoresis. In accordance with previous studies (Salas and Green, 1971; Tsai and

Relationship between cytoagglutination a

Relationship between cytoagglutination and saturation density of cell growth

✍ Joseph Weber 📂 Article 📅 1973 🏛 John Wiley and Sons 🌐 English ⚖ 366 KB

## Abstract The agglutination with concanavalin A and wheat germ agglutinin of the established malignant cells, HEp 2, KB, HeLa, TDB‐3, HTC and RV 3T3, and of the putatively normal cells, BHK 21, 3T3 and Wi‐38 was examined as a function of their saturation densities in culture. A positive correlati

Pyrimidine biosynthesis in normal and tr

Pyrimidine biosynthesis in normal and transformed cells

✍ Uziel, Mayo ;Selkirk, James 📂 Article 📅 1979 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 485 KB

We have developed procedures for sensitive measurement of specific radioactivities of pyrimidine nucleosides excreted from cells in culture. The changes in the observed values reflect dilution of the added isotope through de novo biosynthesis of nonradioactive pyrimidine nucleosides or by shifting a

Relationship between modulus and density

Relationship between modulus and density for high-density closed-cell thermoplastic foams

✍ M. J. Iremonger; J. P. Lawler 📂 Article 📅 1980 🏛 John Wiley and Sons 🌐 English ⚖ 516 KB

The relationship between cell surface pr

The relationship between cell surface protein and glucose and α-aminoisobutyrate transport in transformed chick and mouse cells

✍ Kenneth M. Yamada; Ira Pastan 📂 Article 📅 1976 🏛 John Wiley and Sons 🌐 English ⚖ 212 KB

DNA synthesis, cell proliferation index

DNA synthesis, cell proliferation index in normal and abnormal gallbladder epithelium

✍ Lamote, Jan; Willems, Gerard 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 221 KB

The observation of mitotic figures in the epithelium of the normal gallbladder is exceptional because cell renewal is occurring at a very slow rate. It is only after using 3H-thymidine and autoradiography to observe the cells in DNA synthesis that evidence of a significant epithelial cell replicatio