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Relationship between conformational stability and lyophilization-induced structural changes in chymotrypsin

✍ Scribed by Karen G. Carrasquillo; Cheryll Sanchez; Kai Griebenow

Book ID
111717771
Publisher
Portland Press
Year
2000
Tongue
English
Weight
152 KB
Volume
31
Category
Article
ISSN
0885-4513

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## Abstract The prediction of changes in protein stability and structure resulting from single amino acid substitutions is both a fundamental test of macromolecular modeling methodology and an important current problem as high throughput sequencing reveals sequence polymorphisms at an increasing ra