Relationship between clinical parameters and linear growth in children with cystic fibrosis

Sweat electrolyte and cystic fibrosis mu

Sweat electrolyte and cystic fibrosis mutation analysis allows early diagnosis in Brazilian children with clinical signs compatible with cystic fibrosis

✍ Rabbi-Bortolini, Eliete; Bernardino, Andr�a L.F.; Lopes, Adoris L.; Ferri, Adria 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 24 KB 👁 2 views

A total of 540 individuals with clinical signs suggestive of cystic fibrosis (CF) was studied. The sweat chloride was measured and the DF508, G542X, R553X, and W1282X mutations of the CF gene were screened by polymerase chain reaction (PCR). With this approach the diagnosis of CF was confirmed in 12