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Relationship Between Chemotherapy Response of Small Cell Lung Cancer and P-glycoprotein or Multidrug Resistance-Related Protein Expression

✍ Scribed by T.-C. Hsia; C.-C. Lin; J.-J. Wang; S.-T. Ho; A. Kao

Publisher
Springer
Year
2002
Tongue
English
Weight
240 KB
Volume
180
Category
Article
ISSN
0341-2040

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Human non-small-cell lung cancer (NSCLC) is considered to be a chemotherapy-refractory malignancy. The underlying mechanisms remain rather obscure. The multidrug resistanceassociated protein (MRP), mediating a multidrug resistance (MDR) phenotype, has been reported to be overexpressed in several dru