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Relationship between blood flow and radiostrontium uptake in the healing bone fracture

✍ Scribed by C. Schümichen; L. Mundriziewski; E. Tischler; G. Hoffmann

Publisher
Springer
Year
1979
Tongue
English
Weight
316 KB
Volume
4
Category
Article
ISSN
0340-6997

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✦ Synopsis

The healing of a diaphyseal tibia fracture was followed in the rat. Callus formation, blood flow and Sr-85 uptake were assessed by a ratio comparison of the fractured to the contralateral side. No correlation was found between blood flow and Sr-85 deposition in the callus and the adjacent bone of the same extremity. It is concluded that the deposition of a radiopharmaceutical in bone is primarily related to the presence of calcifiable organic bone matrix and only secondarily to the bone formation rate and to variations in the local blood flow.

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## Abstract Several methods have been employed in the study of bone perfusion. We used a method of determining inert gas wash‐out by mass spectrometry in the study of blood flow rates in pigs. The method was validated by comparison of the result obtained with inert gas wash‐out to that with measure