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Relationship between biological behavior and phenotypic expression in undifferentiated-type gastric carcinomas

✍ Scribed by Akira Kabashima; Takashi Yao; Yoshihiko Maehara; Masazumi Tsuneyoshi


Publisher
Springer
Year
2005
Tongue
English
Weight
940 KB
Volume
8
Category
Article
ISSN
1436-3291

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Relationship between E-cadherin gene mut
✍ Elena Fricke; Gisela Keller; Ingrid Becker; Erika Rosivatz; Christina Schott; Su πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 French βš– 440 KB

## Abstract E‐cadherin mutations are found in 50% of diffuse‐type gastric carcinoma, but not in intestinal gastric carcinoma. Because cell–cell adhesion mediated by E‐cadherin plays an important role in epithelial cell survival, E‐cadherin mutations could alter the apoptotic behavior of tumor cells