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Relationship between antigenic type of virus and antibody response in female patients with herpes genitalis

โœ Scribed by Yoshikatsu Ozaki; Masami Ohashi; Edna Matiko Kimura; Tatsuya Ishiguro

Publisher
John Wiley and Sons
Year
1980
Tongue
English
Weight
437 KB
Volume
5
Category
Article
ISSN
0146-6615

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โœฆ Synopsis

Abstract

The antigenic types of virus recovered from genital sites in cases of adult female genital herpes and antibody response in these patients were investigated. Twelve strains were isolated from 23 clinical specimens, and half the number of the isolates was classified as type 1 virus and the remaining half as type 2 virus. The results of serological typing corresponded well to biological differentiation by plaqueโ€forming ability on chick embryo cultures. The patients with type 1 virus infection had only the complement requiring neutralizing antibody, thus indicating a fresh infection. On the other hand, the noncomplement requiring neutralizing antibody was found in the patients with type 2 virus infection, indicating a later phase of infection.

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โœ M. Krฤmรกล™; A. Suchรกnkovรก; J. Kaลˆka; V. Vonka ๐Ÿ“‚ Article ๐Ÿ“… 1986 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 410 KB ๐Ÿ‘ 1 views

## HERPES SIMPLEX TYPE-2 ANTIBODY IN SERA OF SUBJECTS WHO Paired sera taken from 63 subjects who developed cervical neoplasia in the course of a prospective study on this disease were examined for the presence of herpes simplex virus type 2 (HSV-2) antibody. The first serum was taken at enrolment