Relationship between acquired deficiency of vitamin K-dependent clotting factors and hemorrhage
β Scribed by Rui Yang; Xiaoping Zhang; Wenning Wei; Mei Hong; Yan Yang; Yu Hu
- Book ID
- 107406091
- Publisher
- Springer-Verlag
- Year
- 2010
- Tongue
- Chinese
- Weight
- 375 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0510-9752
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W e describe a female infant who presented with severe intracranial bleeding and was found to have a hereditary deficiency of vitamin K-dependent coagulation factors. She also had mild stippling of the left femoral epiphysis and shortness of the distal phalanges of the fingers. W e studied the possi
All of these factors were determined by one-stage assay using standard technique. Prothrombin by two-stage assay was 12%. Screening forcoagulation inhibitors was negative. Protein C antigen [74% (normal, 70-140 by enzyme-linked immunosorbent assay], protein C 146% by chromogenic assay (normal, 70-14