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Relation between transfection efficiency and cytotoxicity of poly(2-(dimethylamino)ethyl methacrylate)/plasmid complexes

✍ Scribed by Petra van de Wetering; Jong-Yuh Cherng; Herre Talsma; Wim E Hennink

Book ID: 114163299
Publisher: Elsevier Science
Year: 1997
Tongue: English
Weight: 296 KB
Volume: 49
Category: Article
ISSN: 0168-3659
DOI: 10.1016/s0168-3659(97)00059-x

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Background Poly(2-(dimethylamino)ethyl methacrylate) (p(DMAEMA)) can be used successfully for in vitro transfection of different cell lines, including the OVCAR-3 human ovarian carcinoma cell line. The aim of this study was to investigate whether it is possible to transfect OVCAR-3 cells in vivo wit