Relation between lymphatic vessel diameter and clinicopathologic parameters in squamous cell carcinomas of the oral region

✍ Scribed by Atsushi Nakayama; Atsushi Ogawa; Yoshiyasu Fukuta; Keigo Kudo

• Publisher: John Wiley and Sons
• Year: 1999
• Tongue: English
• Weight: 384 KB
• Volume: 86
• Category: Article
• ISSN: 0008-543X
• DOI: 10.1002/(sici)1097-0142(19990715)86:2<200::aid-cncr3>3.0.co;2-#

✦ Synopsis

BACKGROUND.

In an attempt to determine the mechanism of cervical lymph node metastases, the authors studied the relation between lymphatic vessels in or around tumor tissue and lymph node metastases in patients with primary squamous cell carcinoma (SCC) of the oral region by enzyme histochemistry using 5Јnucleotidase-alkaline phosphatase.

METHODS.

The subjects were 23 patients who had biopsy proven oral SCC. After enzyme histochemical staining, the cross-sectional dimension (referred to as diameter) of the lymphatic vessels were measured and analyzed in relation to the T classification of the tumor, degree of tumor differentiation, and mode of invasion.