Primary monolayer cultures of rat hepatocytes at confluence were exposed to an exogenously added source of superoxide, and its influence on collagen synthesis was examined. Superoxide was generated by the addition of dihydroxyfumarate to the culture medium. Exposure of hepatocytes to dihydroxyfumara
β¦ LIBER β¦
Relation between Collagen Synthesis and Collagen Proline Hydroxylase Activity in Mammalian Cells
β Scribed by GOLDBERG, BURTON; GREEN, HOWARD
- Book ID
- 109665849
- Publisher
- Nature Publishing Group
- Year
- 1969
- Tongue
- English
- Weight
- 211 KB
- Volume
- 221
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/221267a0
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## Abstract Atrial natriuretic peptide, besides its role in the regulation of volume homeostasis, has been noted to exert cytoprotective effects in several cell types from hypoxia. The present study was performed to explore the effect of ANP on high glucoseβactivated transforming growth factorβbeta