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Reinvestigation of the transmembrane difference in 7Li NMR T1 values in Li+-loaded human erythrocyte suspensions

✍ Scribed by Duarte Mota De Freitas; Qinfen Rong; Suilan Mo


Book ID
102532401
Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
383 KB
Volume
29
Category
Article
ISSN
0740-3194

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✦ Synopsis


Abstract

In contrast to the findings in a recent study (R. P. Gullapalli, R. M. Hawk, R. A. Komoroski, Magn. Reson. Med. 20, 240 (1991), we found that, even at high hematocrits, the T~1~ values for extracellular ^7^Li were at least three times longer than those for intracellular Li^+^. We conclude that a transmembrane difference in T~1~ values can be used for separate observation of intracellular and extracellular Li^+^ in human red blood cell suspensions.