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Reinterpretation of the breakpoint position of chromosome 18 in t(14;18)

โœ Scribed by E. Nacheva


Book ID
119105031
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
148 KB
Volume
55
Category
Article
ISSN
0165-4608

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The t( 14; 18) chromosomal translocation characteristic of follicular lymphoma (FL) juxtaposes the immunoglobulin heavy chain locus (IGH) and the BCU proto-oncogene. The translocation can be readily detected as a non-germline Not1 fragment resolved by pulsed-field gel electrophoresis. A benefit of t