Reinterpretation of G-banding complex karyotypes by fluorescence in situ hybridization with chromosome-specific DNA libraries and alpha-satellite centromere-specific DNA probes in malignant hematological disorders

Reinterpretation of G-banded complex kar

Reinterpretation of G-banded complex karyotypes by fluorescence in situ hybridization with chromosome-specific DNA painting probes and alpha-satellite centromere-specific DNA probes in malignant hematological disorders

✍ Shi, Guangping; Weh, Hans Josef; Hossfeld, Dieter Kurt 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 901 KB

In this study, we have performed fluorescence in situ hybridization (FISH) with chromosome-specific DNA painting probes 1, 2, 3, 4, 6, 8, and 12 and centromere-specific DNA probes 7, 10, 12, 17, 18, and X after G-banding on the same metaphase spreads from four patients with malignant hematological d