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Reinnervation of rat extensor digitorum longus muscles after free grafting

✍ Scribed by Dr. Bruce M. Carlson; Dr. Kenneth R. Wagner; Dr. Stephen R. Max


Publisher
John Wiley and Sons
Year
1979
Tongue
English
Weight
380 KB
Volume
2
Category
Article
ISSN
0148-639X

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Two types of nerve lesions were performed at birth in rat extensor digitorum longus muscle: sciatic nerve transection (group A) and sciatic nerve crush allowing further reinnervation (group 6). Contractile responses were then studied at different times after the denervation (7, 14, 30, and 60 days)

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Background: In order to understand the cellular basis underlying the progressively poorer restorative capacity of long-term denervated muscle, we determined the effects of long-term denervation on the muscle fibers and satellite cell population of the rat extensor digitorum longus (EDL) muscle. Met