Reinnervation of Adult Rat Gastrocnemius Muscle by Embryonic Motoneurons Transplanted into the Axotomized Tibial Nerve

Long-term delivery of FGF-6 changes the

Long-term delivery of FGF-6 changes the fiber type and fatigability of muscle reinnervated from embryonic neurons transplanted into adult rat peripheral nerve

✍ Robert M. Grumbles; Gizelda T. B. Casella; Michelle J. Rudinsky; Patrick M. Wood 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 659 KB

## Abstract Motoneuron death leads to muscle denervation and atrophy. Transplantation of embryonic neurons into peripheral nerves results in reinnervation and provides a strategy to rescue muscles from atrophy independent of neuron replacement in a damaged or diseased spinal cord. But the count of