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Reining in FoxP3+ regulatory T cells by the sphingosine 1-phosphate-S1P1 axis

✍ Scribed by Kim, Chang H

Book ID
109864887
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
244 KB
Volume
87
Category
Article
ISSN
0818-9641

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## Abstracts **Background:** Sphingosine 1‐phosphate (Sph‐1‐P) is a bioactive lipid mediator released from activated platelets, which regulates diverse signal transduction pathways via cell surface receptors. Recent studies have revealed that the seven‐transmembrane‐spanning receptors, Edg‐1, Edg‐3