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REGγ proteasome mediates degradation of the ubiquitin ligase Smurf1

✍ Scribed by Jing Nie; Min Wu; Jian Wang; Guichun Xing; Fuchu He; Lingqiang Zhang


Book ID
113622049
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
832 KB
Volume
584
Category
Article
ISSN
0014-5793

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## Abstract E6‐associated protein (E6AP) is a cellular ubiquitin protein ligase that mediates ubiquitylation and degradation of tumor suppressor p53 in conjunction with the high‐risk human papillomavirus E6 protein. We previously reported that E6AP targets annexin A1 protein for ubiquitin‐dependent