Regulatory/suppressor T cells in health and disease
β Scribed by Ethan M. Shevach
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 57 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0004-3591
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π SIMILAR VOLUMES
During acute type B hepatitis, the proportion of inducer to cytotoxic/suppressor T-cells is decreased due to an increase in the concentration of suppressor cells. Similar changes are seen in chronically infected subjects with evidence of active viral replication (HBeAg positive) and chronic hepatiti
## Abstract ## BACKGROUND Active suppression by CD4^+^CD25^+^ regulatory T cells plays an important role in the downβregulation of the response of T cells to foreign and self antigens. Experimental tumor models in mice revealed that regulatory T cells inhibit antitumor immune responses. The purpos
The immune system is a delicately balanced network of interacting cells. In recent years, the concept of immune regulation/suppression has been firmly established, and both natural and induced regulatory cells play vital roles in protection from autoimmune disease. Recent work has revealed the diver