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Regulatory volume decrease by cultured non-pigmented ciliary epithelial cells

✍ Scribed by Mortimer M. Civan; Kim Peterson-Yantorno; Miguel Coca-Prados; Robert E.Yantorno


Book ID
117100402
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
935 KB
Volume
54
Category
Article
ISSN
0014-4835

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During exposure to a hypotonic solution (55% osmolarity), cultured human epithelial (Intestine 407) cells exhibit a regulatory volume decrease after osmotic swelling. This process is known to involve parallel activation of volume-regulatory K + and C1-conductances. Biphasic increase in the cytosolic