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Regulatory T cells (CD4+CD25brightFoxP3+) expansion in systemic sclerosis correlates with disease activity and severity

✍ Scribed by Gleb Slobodin; Mohammad Sheikh Ahmad; Itzhak Rosner; Regina Peri; Michael Rozenbaum; Aharon Kessel; Elias Toubi; Majed Odeh


Book ID
113527252
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
308 KB
Volume
261
Category
Article
ISSN
0008-8749

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## Abstract Regulatory T cell responses to infectious organisms influence not only immunity and immunopathology, but also responses to bystander antigens. Mice infected with the gastrointestinal nematode parasite __Heligmosomoides polygyrus__ show an early Th2‐dominated immune response (days 7–14),