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Regulatory Role of Na,K-ATPase in the Growth of Heart Tissue Explants in Organotypic Culture

✍ Scribed by E. V. Lopatina; V. A. Penniyainen; A. A. Zaika


Publisher
Springer US
Year
2005
Tongue
English
Weight
339 KB
Volume
140
Category
Article
ISSN
0007-4888

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It is demonstrated a fast and significant depression in the sarcolemmal (Na,K)-ATPase activity that occurs as early as 25 sec after the onset of Ca2+ depletion, and participates in the development of Ca(2+)-paradox in the rat heart. Pretreatment of the animals with 7-oxo-prostacyclin (PGI2) 24-48 h