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Regulatory Network of Mitomycin C Action in Human Colon Cancer Cells

โœ Scribed by Suzuki, Katsuyuki ;Yamamoto, Wataru ;Park, Ji-Seon ;Hanaoka, Hohken ;Okamoto, Ryo ;Kirihara, Yoshimasa ;Yorishima, Takashi ;Okamura, Tatsunori ;Kumazaki, Tsutomu ;Nishiyama, Masahiko

Book ID
108581763
Publisher
Wiley (Blackwell Publishing)
Year
1999
Tongue
English
Weight
198 KB
Volume
90
Category
Article
ISSN
0910-5050

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โœ Shivendra V. Singh; Domenic Scalamogna; Hong Xia; Stacy O'Toole; Deodutta Roy; E ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 765 KB

This study describes characteristics of a mitomycin C (MMC)resistant human bladder cancer cell line, )82/MMC-2, which was established by repeated in vitro exposures of a 6-fold MMC-resistant variant (J82lMMC) to 18 nM MMC. A 9.6-fold higher concentration of MMC was required to kill 50% of the )82/MM