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Regulatory Natural Killer Cells: New Players in the IL-10 Anti-Inflammatory Response

✍ Scribed by Eric Vivier; Sophie Ugolini

Book ID: 116362454
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 210 KB
Volume: 6
Category: Article
ISSN: 1934-6069
DOI: 10.1016/j.chom.2009.12.001

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## Abstract IL‐18 administration promotes innate immunity resulting in significant antitumor effects in multiple murine tumor models. Here, we examined the effector population mediating the innate immunity. Most NK cells and some NKT cells express IL‐18Rs without prior stimulation (65% positive in