Regulatory experience with the mouse local lymph node assay for skin sensitisation
β Scribed by Peter F. Evans
- Book ID
- 108287380
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 55 KB
- Volume
- 231
- Category
- Article
- ISSN
- 0300-483X
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## Abstract The mouse local lymph node assay (LLNA) has been developed and validated for the identification of chemicals that have the potential to induce skin sensitisation. In common with other predictive test methods the accuracy of the LLNA is not absolute and experience has revealed that a few
## Abstract The murine local lymph node assay (LLNA) is currently recognized as a standβalone sensitization test for determining the sensitizing potential of chemicals, and it has the advantage of yielding a quantitative endpoint that can be used to predict the sensitization potency of chemicals. T