## Abstract BK virus (BKV), a common human polyomavirus infection latent in the kidneys, can reactivate with immunosuppression to cause renal disease. Some have suggested that BKV may contribute to the development of bladder cancer, and BKV sequences have been reported from bladder tumors. To furth
Regulatory DNA sequence conserved in the course of BK virus evolution
โ Scribed by Chie Sugimoto; Kazuya Hara; Fumiaki Taguchi; Yoshiaki Yogo
- Publisher
- Springer
- Year
- 1990
- Tongue
- English
- Weight
- 525 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0022-2844
No coin nor oath required. For personal study only.
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## Abstract Evidence has accumulated indicating that BK virus, following an inapparent primary infection, persists in the renal organs of normal healthy individuals and reactivates upon immunosuppression. Data to support this hypothesis are presented and suggest that BK virus DNA sequences are pres
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Extensive sequencing in the HoxD complex of several vertebrate species has revealed a set of conserved DNA sequences interspersed between neighboring Hox genes. Their high degree of conservation strongly suggested that they are used for regulatory purposes, a hypothesis that was largely confirmed by