𝔖 Bobbio Scriptorium
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Regulatory agency considerations and requirements for validation of toxicity test alternatives

✍ Scribed by Green, Sidney


Book ID
123040765
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
313 KB
Volume
68
Category
Article
ISSN
0378-4274

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Validation of intratracheal instillation
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In collecting inhalation toxicity data for the evaluation of the health hazard from occupational exposure to the aerosols of a drug or a chemical, the determination of the inhaled dose in relation to the animal response is most desirable. Intratracheal administration is most likely to deliver an exa