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Regulator of G protein signaling–2 and control of vascular tone in bartter's/gitelman's sydrome

✍ Scribed by Lorenzo A. Calo; Elisa Pagnin; Paul A. Davis; Michelangelo Sartori; Achille C. Pessina; Andrea Semplicini


Book ID
116208062
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
49 KB
Volume
17
Category
Article
ISSN
0895-7061

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## Abstract Regulator of G‐protein signaling‐2 (RGS‐2) belongs to a novel family of GTPase‐activating proteins that rapidly turn‐off G‐protein coupled receptor signaling. RGS proteins contain a characteristic RGS domain by which they interact with the α‐subunit of G‐proteins and drive them into the