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Regulative influence of o-aminobenzoic acid on the biosynthesis of nourseothricin in cultures of Streptomyces noursei JA 3890b IV. Bistability of metabolism and the mechanism of action of aminobenzoic acids

✍ Scribed by Dr. U. Gräfe; H. Bocker; H. Thrum

Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
853 KB
Volume
19
Category
Article
ISSN
0233-111X

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Regulative influence of o-aminobenzoic a
Regulative influence of o-aminobenzoic acid (OABA) on the biosynthesis of nourseothricin in cultures of Streptomyces noursei JA 3890b. V. Effect of OABA on cytochrome levels and amino acid transport
✍ Dr. U. Gräfe; A. Steudel; H. Bocker; H. Thrum 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 561 KB

## Abstract __o__‐Aminobenzoic acid (OABA) known by its stimulatory effect on streptothricin biosynthesis by __Streptomyces noursei__ JA 3890b was found to suppress specifically the formation of cytochrome __a__‐type terminal oxidase while the levels of the __b__‐ and __c__‐type cytochromes apparen

Regulative influence of o-aminobenzoic a
Regulative influence of o-aminobenzoic acid on the biosynthesis of nourseothricin in cultures of Streptomyces noursei JA 3890b II. Regulation of glutamine synthetase and the role of the glutamine synthetase/glutamate synthase pathway
✍ Dr. U. Gräfe; H. Bocker; H. Thrum 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 656 KB

## Abstract In __S. noursei__ JA 3890b which produces nourseothricin, a streptothricin‐type antibiotic, the participation of the glutamine synthetase/glutamate synthase pathway in the regeneration of glutamic acid was established. Glutamate synthase of this organism requires 2‐ketoglutarate, gluta