Regulation of δ-crystallin expression: Interaction of nuclear factors and the lens-specific enhancer
✍ Scribed by H. Kondoh; J. Funahashi; R. Sekido; Y. Kamachi
- Book ID
- 115895046
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 117 KB
- Volume
- 55
- Category
- Article
- ISSN
- 0014-4835
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There are two tandemly linked dcrystallin genes (58 d1-d2 38) in the chicken, with the d1-crystallin gene being expressed much more highly (50-100-fold) in the embryonic lens than the d2crystallin gene. Previous transfection experiments have shown that a lens-preferred enhancer exists in the third i
## Abstract Tissue specific regulation of gene expression by a single transcription factor or group of transcription factors cannot be explained simply by DNA sequence alone. For example, in the same animal a particular transcription factor is capable of interacting with DNA in the nucleus of many