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Regulation of volume-sensitive Cl− channels in multi-drug resistant MCF7 cells

✍ Scribed by Matthieu Marin; Agnès Poret; Géraldine Maillet; François Leboulenger; Frank Le Foll


Book ID
116290972
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
675 KB
Volume
334
Category
Article
ISSN
0006-291X

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## Abstract The platinum‐based drug cisplatin is a widely used anticancer drug which acts by causing the induction of apoptosis. However, resistance to the drug is a major problem. In this study we show that the KCP‐4 human epidermoid cancer cell line, which serves as a model of acquired resistance