Regulation of virus-triggered type I interferon signaling by cellular and viral proteins
β Scribed by Bo Zhong; Yan-Yi Wang; Hong-Bing Shu
- Book ID
- 107382772
- Publisher
- SP Higher Education Press
- Year
- 2010
- Tongue
- English
- Weight
- 311 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1674-7984
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Therapeutic use of type I IFN (IFN- Β§ / g ) has become common. Many of the diverse diseases targeted are marked by pathogenetic abnormalities in cell-mediated immunity (CMI), these cellular immune responses either causing injury to the host, lacking sufficient vigor for virus or tumor clearance, or
## Abstract Measles virus (MV) causes transient but profound immunosuppression resulting in increased susceptibility to secondary bacterial and viral infections. Due to the development of these opportunistic infections, measles remains the leading vaccineβpreventable cause of child death worldwide.