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Regulation of vascular endothelial growth factor transcription by endothelial PAS domain protein 1 (EPAS1) and possible involvement of EPAS1 in the angiogenesis of renal cell carcinoma

✍ Scribed by Guangbin Xia; Yukio Kageyama; Tetsuo Hayashi; Satoru Kawakami; Mitsuaki Yoshida; Kazunori Kihara


Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
167 KB
Volume
91
Category
Article
ISSN
0008-543X

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The formation of new vessels (angiogenesis) is essential for primary tumour growth and metastasis and is induced by several angiogenic factors, including vascular endothelial growth factor (VEGF). The microvascular density (MVD) in tumours was assessed and the expression of VEGF and its receptors VE