Regulation of uridine kinase activity in BLAB/C-3T3 cells by serum components
โ Scribed by Walker Wharton; W. J. Pledger
- Book ID
- 112801032
- Publisher
- Society for In Vitro Biology
- Year
- 1981
- Tongue
- English
- Weight
- 493 KB
- Volume
- 17
- Category
- Article
- ISSN
- 1475-2689
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๐ SIMILAR VOLUMES
The effects of the anti-cancer anthracyclines doxorubicin and daunorubicin on the activity of protein kinase C (PKC) were examined in intact Swiss 3T3 cells. The 2 drugs stimulated the phosphorylation of an 80K phosphoprotein found to be identical to that generated in response to the PKC activator 1
The effect of inhibition of the cell membrane Na+-K+ pump on the Balbk-3T3 cell growth cycle was studied. Inhibition of the Na+-K+ pump resulted in a dose-dependent reduction of intracellular K+ concentration ({Kf},). However, inhibition of protein synthesis in Gi/G, and of subsequent entry into S p