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Regulation of tyrosine hydroxylase and tetrahydrobiopterin biosynthetic enzymes in PC12 cells by NGF, EGF and IFN-γ

✍ Scribed by Panagiotis Z. Anastasiadis; Donald M. Kuhn; Jennifer Blitz; Bruce A. Imerman; Marisa C. Louie; Robert A. Levine

Book ID
113128189
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
914 KB
Volume
713
Category
Article
ISSN
0006-8993

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Aromatic l-amino acid decarboxylase (AADC) and tyrosine hydroxylase (TH) are involved in the synthesis of dopamine and other monoamine neurotransmitters, and their activities can be regulated by a number of physiological stimuli. An interesting finding has been that (2)-deprenyl and some other irrev