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Regulation of tyrosine hydroxylase and aromatic l-amino acid decarboxylase by dopaminergic drugs

โœ Scribed by Seongeun Cho; Norton H Neff; Maria Hadjiconstantinou

Book ID
119413721
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
351 KB
Volume
323
Category
Article
ISSN
0014-2999

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Reciprocal regulation of the content of
Reciprocal regulation of the content of aromatic L-amino acid decarboxylase and tyrosine hydroxylase mRNA by NGF in PC12 cells
โœ X.-M. Li; J. Qi; A.V. Juorio; A.A. Boulton ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 86 KB

Aromatic l-amino acid decarboxylase (AADC) and tyrosine hydroxylase (TH) are involved in the synthesis of dopamine and other monoamine neurotransmitters, and their activities can be regulated by a number of physiological stimuli. An interesting finding has been that (2)-deprenyl and some other irrev