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Regulation of type V adenylyl cyclase by PMA-sensitive and -insensitive protein kinase C isoenzymes in intact cells

✍ Scribed by Jun-ichi Kawabe; Toshiaki Ebina; Yoshiyuki Toya; Naoki Oka; Carsten Schwencke; Emir Duzic; Yoshihiro Ishikawa


Book ID
117980367
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
358 KB
Volume
384
Category
Article
ISSN
0014-5793

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## Abstract 1,25‐Dihydroxyvitamin D~3~ (1,25(OH)~2~D~3~) treatment of osteoblastic cells was shown previously to attenuate Parathyroid hormone (PTH) response by inhibiting adenylyl cyclase (AC) activity. In this study, we have investigated the mechanism by which 1,25(OH)~2~D~3~ inhibits AC in rat o