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Regulation of tumor suppressors by nuclear-cytoplasmic shuttling

✍ Scribed by Megan Fabbro; Beric R Henderson


Book ID
117099713
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
286 KB
Volume
282
Category
Article
ISSN
0014-4827

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## Abstract RUNX/AML transcription factors are critical regulators of cell growth and differentiation in multiple lineages and have been linked to human cancers including acute myelogenous leukemia (RUNX1), as well as breast (RUNX2) and gastric cancers (RUNX3). RUNX proteins are targeted to gene re