## Abstract ## BACKGROUND Vascular endothelial growth factor (VEGF)βA and angiopoietin (Ang)β1 and Angβ2 are key factors in angiogenic signaling. In this study the expression of these factors was identified in cartilage tumors. As interleukin (IL)β1Ξ² has been found to be an indispensable factor in
Regulation of tumor dormancy as a function of tumor-mediated paracrine regulation of stromal Tsp-1 and VEGF expression
β Scribed by SOO-YOUNG KANG; RANDOLPH S. WATNICK
- Book ID
- 109343875
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 166 KB
- Volume
- 116
- Category
- Article
- ISSN
- 0365-5555
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Recent studies demonstrate that PI3K activation and PTEN mutation are frequently found in many human cancer cells and tissues. However, the mechanism of PI3K signaling in human cancer tumorigenesis remains to be elucidated. In this study we specifically downregulated p110Ξ± expression in
Tumor necrosis factor Ξ± (TNF-Ξ±) promotes bone loss and inhibits bone formation. Osterix (Osx, SP7) is a transcription factor required for osteoblast (OB) differentiation because deletion results in a cartilaginous skeleton. We previously described a TNF suppressor element in the Osx promoter that wa