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Regulation of Transformed State by Calpastatin via PKCϵ in NIH3T3 Mouse Fibroblasts

✍ Scribed by Takaki Hiwasa; Mitsuyuki Nakata; Miho Nakata; Shigeo Ohno; Masatoshi Maki; Koichi Suzuki; Masaki Takiguchi

Book ID
117979378
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
376 KB
Volume
290
Category
Article
ISSN
0006-291X

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## Abstract Protein kinase C epsilon is an oncogenic, actin nucleating protein that coordinately regulates changes in cell growth and shape. Cells constitutively expressing PKCϵ spontaneously acquire a polarized morphology and extend long cellular membrane protrusions. Here we report that the regul