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Regulation of the specificity of the 26S proteasome endoribonuclease activity in K562 cells under the action of differentiation and apoptosis inducers

โœ Scribed by A. G. Mittenberg; T. N. Moiseeva; I. V. Pugacheva; V. A. Kulichkova; A. S. Tsimokha; L. N. Gause; I. M. Konstantinova

Book ID
111471389
Publisher
Pleiades Publishing
Year
2007
Tongue
English
Weight
230 KB
Volume
1
Category
Article
ISSN
1990-519X

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The multicatalytic protease complex or proteasome is a fundamental nonlysosomal tool that the cell uses to process or degrade proteins at a fast rate through the ubiquitin and ATP-dependent proteolytic pathway. Examples of these important proteins include the tumor suppressor protein p53, various cy