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Regulation of the salvage pathway of purine nucleotide synthesis by the oxidation state of NAD+ in rat heart cells

✍ Scribed by Katy Ravid; Paula Diamant; Yoram Avi-Dor


Book ID
115706059
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
728 KB
Volume
229
Category
Article
ISSN
0003-9861

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The capacity of the oxidative pentose pathway (PPP) in the heart is limited, since the activity of glucose-6-phosphate dehydrogenase (G-6-PD), the first and regulating enzyme of this pathway, is very low. Two mechanisms are involved in the regulation of this pathway. Under normal conditions, G-6-PD