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Regulation of the rat CYP4A2 gene promoter by c-Jun and octamer binding protein-1

✍ Scribed by Eva Fiala-Beer; Andy C. Lee; Michael Murray

Book ID
116307380
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
772 KB
Volume
39
Category
Article
ISSN
1357-2725

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## Abstract Hypoxic injury to the ocular surface provokes an inflammatory response that is mediated, in part, by corneal epithelial‐derived 12‐hydroxyeicosanoids. Recent studies indicate that a cytochrome P450 (CYP) monooxygenase, identified as CYP4B1, is involved in the production of these eicosan